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In preparing tissues for histology or histopathology, D-limonene is often used as a less toxic substitute for xylene when clearing dehydrated specimens.
Limonene is a colourless liquid hydrocarbon classified as a cyclic terpene. The more common D-isomer possesses a strong smell of oranges It is used in chemical synthesis as a precursor to carvone and as a renewables-based solvent in cleaning products.
Hazard Class: 3
Packing Group: 3
Hazard Phrases: Flammable liquid and vapour. Causes skin irritation. May cause an allergic skin reaction. Very toxic to aquatic life with long lasting effects. May be fatal if swallowed and enters airways.
Prec Phrases: Keep away from heat/sparks/open flames/hot surfaces. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Do NOT induce vomiting. IF ON SKIN: Wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention. Wear protective gloves/protective clothing/eye protection/face protection.
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