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We can only ship non-hazardous products to Rest of World

DL-Dithiothreitol

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Price: £11.02

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Stock Availability

On Shelf - Approx. UK delivery date: Wednesday the 17th September 2025*

In bulk stock - ships within 10 - 12 Working Days (Excluding weekends and public holidays)

4 to 6 weeks approx. (Not guaranteed)

UK Shipping

Unfortunately, we are not currently accepting orders for Northern Ireland.

We can only ship to the following postcodes where a Royal Mail postal option has been chosen at checkout.

AB, DD, DG3, DG4, DG6 - DG9, EH, FK, G, HS, IM, IV, KA, KW, KY, ML, PA, PH, PO30 - PO41, TD, TR21 - TR25, ZE

* We will always try to ship as early as possible. Delivery could be much quicker than stated but is not guaranteed

Applications

SDS-PAGE
Mass spectrometry analysis
DNA research

General

What is DL-Dithiothreitol? It is a chemical compound primarily used as a reducing agent in various scientific and biochemical applications. Its main function is to reduce disulphide bonds in proteins and other molecules, preventing unwanted oxidation and maintaining thiol groups in their reduced state.

Consistent Quality: We provide only high-quality DL-Dithiothreitol, ensuring reliable and consistent performance for all applications.

Shipped from Manchester, UK Facility: Sourced and packaged in non-toxic, chemical-resistant containers to ensure safe handling and preserve product quality during transport.

Frequent Uses

Reducing Protein Disulfide Bonds
DTT is a key reagent in sample buffers for SDS-PAGE (sodium dodecyl sulphate polyacrylamide gel electrophoresis), where it reduces disulphide bonds in proteins, facilitating their separation based on size.

Maintaining Reduced Thiols
Used to prevent the oxidation of thiol (-SH) groups in proteins and other molecules, which is crucial for maintaining their activity and preventing unwanted aggregation.

In-solution Protein Digestion
Used in proteomics for digesting proteins in solution prior to mass spectrometry analysis.

Enzyme Stabilisation
Can act as an enzyme stabiliser by preventing the modification of DNA.

Specification

Assay: 99.0 - 102.%
M.F.: C4H10O2S2
M.W.: 154.25g/mol
F.P.: 113 °C

Hazards

Hazard Phrases: Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Prec Phrases: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Harmful CLP Image